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Liverpool need eight more wins to secure the Premier League title and do not look like letting up.
The routine 2-0 win at West Ham was their eighth in nine in midweek - including a 3/1 winner thanks to Alex Oxlade-Chamberlain - and they are incredibly strong at Anfield.
Although their defence has been so good, Southampton have also been one of the league's form teams with just one defeat in their last seven. Ralph Hasenhuttl's side have performed some turnaround after looking doomed for relegation and the Austrian, compared to Klopp in his early days in England, deserves huge credit for that.
A big driving force behind that is 16-goal striker Danny Ings, formerly of Liverpool and he is 13/5 to score anytime.
But the preference is to look at the handicaps. Liverpool should win, but Southampton can score and at least run them close. With the expectation of a one-goal home win, backing the visitors on a +2 handicap at around evens looks a favourable option.
Score prediction: Liverpool 2-1 Southampton ()
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Steve Bruce's injury crisis at Newcastle is hardly easing with up to nine absentees, but with the return of star winger Allan Saint-Maximin and new signing Nabil Bentaleb in midfield they still have enough to continue their strong record at St James' Park.
Last time out in front of their fans, they snatched a late win over Chelsea to take their home points to 19 points - top half form - and they welcome the Canaries, who have the worst away record and are heading for a swift return to the Championship.
Bruce's side have shown grit and even Miguel Almiron has started to chip in with a couple of goals. They are set up well and should contain Norwich, who rely too much on Teemu Pukki in the final third. A home, low-scoring win at 2/1 looks good here.
Score prediction: Newcastle 2-0 Norwich ()
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Odds correct as of 1700 GMT on 30/01/20
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