Manchester City paid the price for not being at their best in the first leg, with Tottenham rising to the occasion on their first European outing in their new ground with a 1-0 win.
Mauricio Pochettino's side have one foot in the Champions League semi-finals, what an achievement that would be given the fact the Argentinian did not spend a penny on his squad last summer.
The one negative for them from last week's tie is the season-ending injury suffered by Harry Kane, but the north Londoners showed at the weekend - albeit against struggling Huddersfield - that they can score without him as they netted four, including a Lucas Moura hat-trick. That is in addition to earlier in the season, when Kane missed a large chunk of action and Heung-min Son rose in his absence to help them maintain a surprise title charge which has, of course, since gone by the wayside.
It was a surprise to see Kevin De Bruyne on the bench for the first leg and the Belgian should be restored for this huge match, with their quadruple hopes on the line.
It should be a cracker. Both sides have nothing to lose and everything to gain. They will be sick of the sight of each other by end of play on Saturday lunchtime, when they meet again in the Premier League at the Etihad.
City did not get a vital away goal in last week's first leg, while a one-goal lead is too dangerous for the visitors to be satisfied with and Hugo Lloris says his team-mates are 'ready to suffer'.
Spurs will not just go to sit on a 1-0 lead. That's just not their style. So plenty of chances could be on the cards at both ends and the odds-against price on Tottenham to register at least four shots on target stands out.
They average six shots on target per game in the competition this term and can find weaknesses to exploit in Pep Guardiola's side. Four shots on target is not much to ask, so it is a great price to get on.
Considering how fast City can burst out the blocks, and how eager they will be to get ahead in this tie, the 27/20 on them to be leading after 30 minutes also stands out, but the preference is to back Spurs chances in the shots on target market.
Score prediction: Man City 3-2 Spurs ()
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