Tuesday's second Premier League match-up is a dead rubber.
Southampton are safe from relegation after Fulham's defeat on Monday night, while visiting side Crystal Palace secured another season in the top-tier with a convincing 2-0 win at Sheffield United.
The Saints were defeated 2-0 by Champions League-chasing Liverpool on Saturday night, extending their winless streak in all competitions to five.
However, a shorthanded Ralph Hasenhüttl side put in a better performance than the scoreline suggests, finding Alisson in fine form after creating chances equating to 1.35 expected goals (xG) at Anfield.
Victory in this game would ensure survival, but motivation alone won't guarantee success against a Palace team who have looked sharp recently, so the match odds should be avoided despite the circumstances.
Instead, there are a couple of intriguing prices in the TIME OF FIRST GOAL market, notably 0:00 - 9:59 at 7/2 and 10:00 - 19:59 at 9/2 on Sky Bet.
In Crystal Palace's 34 league matches this season, a total of 22 goals have been scored in the opening 20 minutes, an astonishing amount for a team that is thought of as being pragmatic.
Odds correct at 1300 BST (10/05/21)
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