We're now at the stage of the season where most teams have little to play for and this game is no exception. Fulham are already relegated while Manchester United will finish in the top-four - although a win here will guarantee their spot as runners-up to champions Manchester City.
One disappointing factor for United is their home form this season. They sit as the fifth-best home side in the division with just one game left to change that but they have enjoyed more success on the road. It's something they will need to address if they are to seriously contend for the title.
Fulham shouldn't cause them too many issues based on their showings this season. Scott Parker's side have won just five of their 38 top-flight games this season and they will, once again, have to look to build in the Sky Bet Championship. This is their final chance to claim a major scalp before dropping down a division.
Apart from wins away at Leicester and Liverpool, Fulham's form against the better sides isn't great. They've lost seven of their 11 games against the current top-six with six of those seeing them fail to score. However, the absence of Harry Maguire may give them a route to goal.
Fulham aren't prolific scorers from set-pieces, although Manchester United struggle to defend them and that is made even worse by Maguire's absence. The centre-back averages four successful aerial duels per game - the duo of Victor Lindelof and Eric Bailly combine for 3.9.
This led to a successful 30/1 tip for Caglar Soyuncu to score anytime in Leicester's win at Old Trafford last week, and the showings of Liverpool in their 4-2 win just days later gives hope that more set-piece goals could come against United before the season ends.
The Fulham defender sits just outside the top-ten for successful aerial duels among centre-backs in the Premier League this season so he has had opportunities to score. His shots count is also something that has developed significantly as the season has progressed.
Andersen's first 19 games brought just one shot - that came in his debut at West Brom. However, his last 11 games have seen a total of 12 shots. They have been coming against top-six sides too, with a shot away at Chelsea and one in the narrow home defeat to Tottenham during this run.
Even with a Fulham goal, it's difficult to look past a home victory here, even with their form at Old Trafford being a small cause for concern compared with where they want to be. Fulham may have seen the majority of their points come on the road but I'm willing to side with their overall record against the top-six.
A finish in second will signal a decent enough season for United, who are likely to have one eye on the Europa League final at the end of the month. They may be made to worry on Tuesday night though, and ANDERSEN represents value given the past week for the hosts.
Score prediction: Manchester United 3-1 Fulham ()
Odds correct at 1100 BST (17/05/21)
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