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Our outright tip for success in this competition get their campaign underway at the earlier time of 17:55 BST away at Qarabag.
Sevilla currently top LaLiga after a fine start in Spain and will be full of confidence as they head into a group that should cause them little issues.
As explained in outright preview, a positive summer of change for Sevilla should put them in a great position in Europe:
This summer has been one of big change for Sevilla and it puts them in a strong position to claim back what seems to be rightfully theirs.
They've seen Wissam Ben Yender, Luis Muriel, Quincy Promes and Pablo Sarabia all depart for fees of above €15m and they were unafraid to reinvest that money on replacements.
Rony Lopes, a winger from Monaco, and Bordeaux's Jules Kounde were the headline signings after joining for a combined €50m fee.
Los Rojiblancos also welcomed Diego Carlos, Moanes Dabour and Joan Jordan among the 15 players that made the switch to Sevilla in the summer.
In total, the Spanish side spent over €156m in this window. It's put them in an incredibly strong position and it's why they've started the new LaLiga campaign with two wins and a draw.
One of those players mentioned is Jordan, who has already struck two times from central midfield in LaLiga.
Not only does he pose a threat from open play, but the midfielder also has a strong ability from set-pieces and will be trusted with Sevilla's chances from close range.
At a price of 15/4, it's worth backing Jordan to score in 90 minutes as opposed to the huge odds-on price on an away victory.
Best bet:
Another side fancied for a strong Europa League campaign is Rennes. They line-up in Group E alongside Lazio, Cluj and Thursday's opponents Celtic.
They welcome the Scottish champions to Roazhon Park on the back of a 0-0 draw away in Brest last time out, but they will still fancy their chances of victory in front of their own supporters.
Celtic may have dominated on the domestic front, but their away efforts in the Europa League last season left a lot to be desired.
They were successful in their group stage clash away at Rosenborg, but were beaten by Salzburg, Leipzig and then Valencia.
Their best chance of progression will come from victories at home, and the same applies to Rennes, which is why the value is with the home team at a price of odds-against.
We have Rennes as group winners here and a price of 9/2 is still available on them to do so. As explained in our outright preview:
Rennes secured a spot in Europe with success in the Coupe de France - beating Lille and Lyon en route to the final where they saw off Paris Saint-Germain on penalties.
They've also started the new campaign in good fashion with three wins from four. Much like last season's Cup final, they have got the better of PSG with a 2-1 victory in mid-August.
They may have lost Ismaila Sarr to Watford over the summer, but they've reinvested the money gained from that sale to bring in players throughout the squad.
The forward positions have benefited the most with two new wingers and a striker joining in the window. The headline addition being Raphinha from Sporting, a right winger who had direct involvement in 12 goals last season despite his young age.
M'Baye Niang will lead the attack having swapped Torino for France. The striker has hit the ground running with two goals in four games; complimenting the 14 he netted in Italy during 2018/19.
Flavien Tait will also add options to the attack. He had a hand in 14 goals last season for Angers in Ligue 1. Primarily a left-winger, the 26-year-old can also play a central role when required.
Best bet:
Odds correct at 1515 BST (17/09/19)
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