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I have had an eye on this game for a while with a goalscorer in mind at around 9/2, until he picked up an injury against Liverpool to keep him sidelined for around three weeks.
A blow for both our Premier League tips and for Tomas Soucek so early in his West Ham career, but we shall stick with the goals market and with another Hammers player.
David Moyes' side are in desperate need of a win as they sit in the final relegation spot, but a repeat performance of Monday's defeat at Liverpool should go some way to delivering that here.
The trouble is that they are inevitably going to raise their game against the league leaders, but against a fellow bottom-half side in front of your own nervy fans it is a different question.
Ralph Hasenhuttl's Saints have been better away from home this term, collecting 20 of their 34 points. Only the current top four have a better away record and that is why they go into the game as 13/8 favourites.
They are prone to a lapse, though, and you cannot back them at this price. There is hope from West Ham that they can continue their display and this squad looks too strong overall to go down.
The interest is with the stand-in striker Michail Antonio, with the utility man preferred to lead the line over expensive summer buy Sebastian Haller.
With Antonio in this role, the 3/1 anytime price looks overpriced (with the system probably still believing he is a winger) and it is therefore worth a small play.
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Odds correct as of 1700 GMT on 27/02/20