Brighton and Hove Albion v Tottenham Hotspur (1945 BST, Sky Sports Football)

Tottenham lost their first Premier League match of 2018 at the weekend and Mauricio Pochettino sent a stark wake-up call to his team ahead of their midweek trip to Brighton.

The north Londoners's previous loss came in December at Manchester City, before going on an impressive 14-game unbeaten run in the league, ending on Saturday in the reverse match with Guardiola’s side at Wembley, who have since been crowned champions.

The Citizens were better in every department, keeping Harry Kane quiet and restricting the England marksman to just six second-half touches. Two quick-fire goals from Gabriel Jesus and Ilkay Gundogan inside the opening 25 minutes set City on their way, with Christian Eriksen pulling one back before half-time rather fortuitously before Raheem Sterling made it three on 72 minutes.

It leaves Pochettino’s side, who have Saturday’s FA Cup semi-final with Manchester United also to consider, fourth in the Premier League standings with five games to go.

The Argentinian boss will be keen to make sure his side do not slip up and let fifth-placed Chelsea close the seven-point gap, yet he will know the threats Chris Hughton’s Brighton possess after beating Arsenal at the Amex only last month.

The Seagulls currently sit 13th, seven points above the bottom three – a nice cushion but Hughton will want to get close to the 40-point mark which usually ensures safety.