Guardiola has managed Barcelona, Bayern Munich and Manchester City, overseeing some fantastic sides since taking over at the Nou Camp a decade ago.
Meanwhile, Klopp has only managed Liverpool in England, after starting out at Mainz before helping Borussia Dortmund to the Bundesliga title and the 2013 Champions League final.
Over the last couple of weeks at Sporting Life we have put together both managers' all-time XIs - and now we want to know whose is best in the ultimate head to head.
Take a look, below, and click the links to see the full articles for the reasons behind players' inclusions before casting your vote via our or .
Last updated at 1430 BST 09/04/2018.